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Brimonidine (Erythego)

Brimonidine Topical Gel 0.33% (Erythego) 15g is the prescription solution to deal with rosacea.  It is a common skin concern that develops flushing of the face and visible blood vessels.
Alternative Search: Erythego
Category: Brimonidine
Active substance: Brimonidine
Prescription: Upload Prescription or Fill Medical Questionnaire Form
Manufacturer: Akumentis Healthcare Ltd
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Brimonidine (Erythego) 15g

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Usage

What is Brimonidine Topical Gel 0.33% (Erythego) 15g?

Brimonidine Topical Gel 0.33% (Erythego) 15g is the prescription solution to deal with rosacea. 

It is a common skin concern that develops flushing of the face and visible blood vessels.

A topical gel is rich in an active ingredient known as Brimonidine. The main aim of this gel is to minimize redness.

People with rosacea can use this gel to take care of symptoms and enhance the skin look and appearance.

Such a problem often occurs because of the enhanced blood flow to facial skin, resulting in skin redness.

Before using it, people must go through an erythego gel review to know more about gel, how it functions, how it treats conditions, dosage, side effects, and others.

The topical gel gives the maximum comfort and assurance to patients with rosacea. Patients add it to their beauty regimen and relieve stress. 

It enables people to feel even skin tone and helps in managing and calming rosacea prone skin.

 When using topical gel, people follow the doctor's instructions and apply it properly to control the symptoms.

Applying the gel in the affected area can aid the patient in minimizing the risk of symptoms and boost the skin's look.

It is an effective barrier to prevent the skin redness and helps people enhance their quality of life. 

How does Brimonidine Topical Gel 0.33% (Erythego) 15g work?

 When it comes to rosacea treatment, people must understand more about the gel and how it works to handle such an issue.

Brimonidine topical gel acts by toning the blood vessel and minimize the redness. 

Patients use it to narrow small blood of skin, diminish the blood flow to the skin, and prevent the excess skin flushing and redness.

Gel lets people to relieve symptoms like swelling, redness and pimples. 

After applying the gel, patients feel better. Patients must take it as long as possible, as suggested by the physician.

Patients receive the maximum benefits very soon by following doctor advice and dosing instructions.

Patients can feel improvement in their condition quickly and speak with doctors to know their condition status.

How to use Brimonidine Topical Gel 0.33% (Erythego) 15g?

The following information provides general information about how this medication is typically taken. Your specific instructions may vary based on your condition and treatment regimen.

  • Brimonidine (Erythego) should be applied only on facial skin.
  • Clean and dry your face prior to the application of the gel.
  • Use the medication once a day unless other instructions are provided by your dermatologist.
  • Apply a small amount (pea-sized) to each of the five areas of the face: the center of forehead, chin, nose, and cheeks.
  • Distribute the gel evenly in thin layer on the areas of the face.
  • Do not apply the gel on the eyes, eyelids, lips, mouth, inner surface of the nose, and other mucous membranes.
  • Do not apply the gel on irritated skin, skin injuries, cuts, and recently treated areas of skin.
  • Wash your hands right after application of the gel.
  • Allow the gel to dry prior to application of other cosmetic and skin care products including sunscreens.
  • Do not apply more than once a day and use no more than the prescribed dose.
  • Do not cover the areas of application with occlusive dressings.
  • In case you missed a dose, apply the next dose according to the regular schedule. Do not apply an extra dose of the medicine to compensate the missed dose.
  • Stop using the gel and contact your doctor in case of development of severe redness, flushing, burning, or swelling of the face.
  • Keep the medicine away from children. Its accidental ingestion, especially by children, may cause severe adverse reactions including low blood pressure, decreased breathing rate, increased drowsiness, weakness, or seizures and require immediate medical assistance.

The information provided above is of general character and should not substitute the professional medical advice. Follow the instructions provided by your health care provider.

Usage /Indications

Erythego contains brimonidine tartrate, a topical alpha-2 adrenergic agonist indicated to treat persistent facial redness of rosacea in adults aged 18 years or older. Erythego is available in a form of gel with 5 mg brimonidine tartrate per gram of product, which equals approximately 3.3 mg brimonidine base per gram of the product. It corresponds to FDA-approved brimonidine topical gel 0.33% formulation.

Brimonidine causes temporary vasoconstriction of superficial blood vessels of facial skin. As a result, excessive blood flow is decreased and persistent redness associated with rosacea becomes less visible. The medication only treats redness of rosacea; it does not cure the disease or its acne-like lesions, visible blood vessels, or eye symptoms.

Redness-reducing effect of Brimonidine (Erythego) is temporary and may vary from patient to patient. Increased redness, flushing, or burning sensation may occur in some patients after application. In case of worsening of facial redness or its spreading outside the area of treatment, the treatment should be reevaluated.

Consult your doctor if symptoms do not improve or persist despite using the medication.

Missed dose

Patients must pay attention to dosage instructions provided by physicians. The required dose is the pea-sized amount that applies to the area regularly.

Applying a missed dose of gel as quickly as possible is essential. Patients skip missed doses whether it is the time for the next dose.

Patients don't use skipped doses that result in side effects during the next scheduled dose.

Don't apply double doses simultaneously that enhance the irritation on the skin.

Overdose

If you accidentally apply more on the skin, you can contact a medical expert immediately and get medical help.

Patients don't need more or less than recommended which causes adverse effects on the skin and worsens the condition.

Overdose can cause adverse effects include

  • Redness
  • Irritation

Usual Dosage

Dosage depends on condition, age, weight, function of organs and systems, and the response to the treatment.

The most common dosing instructions for official Brimonidine prescribing information include application of the pea-sized amount once daily to the five facial areas: the center of forehead, chin, nose, left cheek, and right cheek. The gel should be distributed evenly in a thin layer on the whole area of the face without applying it to the eyes and lips.

The daily dose should not exceed approximately 1 g of gel. Application of more Brimonidine and/or frequent use of the medication will not necessarily improve redness but will increase the risk of skin irritation, flushing, hypotension, dizziness, and other systemic effects.

Brimonidine topical gel is approved only for use in adults aged 18 years and older. Safety and efficacy of Brimonidine have not been established in children. It should be used externally only for facial application and should not be used in eyes, mouth, vagina, or any other areas of the body.

The therapy can be used daily for the duration specified by your physician. Since this medicine affects redness temporarily and does not cure rosacea, the redness can appear again after wearing off of the effect of the medicine. If patients experience persistent worsening of redness, they should discontinue the treatment and seek medical advice.

The physician will select the most appropriate dosage and treatment regimen for your condition.

Precautions and warnings

Before using topical gel for rosacea, patients let doctors know whether they are allergic to any medical conditions and allergies.

It may also come with an inactive ingredient that develops health issues and allergic reactions.

Patients must inform their doctor about medical history, like

  • Liver
  • Kidney
  • Heart disease
  • Allergy
  • Cuts and wounds in the skin
  • Decreased blood supply
  • Depression
  • Fall in blood pressure
  • Poor blood circulation
  • Sjogren syndrome
  • Any laser procedure

Doctors never recommend erythego gel to pregnant and breastfeeding women because it affects the foetus and little one.

After using topical gel, patients don't drive vehicles or operating machines. If you have the above problems, you must use it with the proper caution. 

During the initial consultation, patients must inform their medical condition to the doctor and get gel with the recommended dose.

Side effects of Brimonidine Topical Gel 0.33% (Erythego) 15g

The possible adverse reactions of Brimonidine (Erythego) include:

  • Increase in redness of the face
  • Flushing/warmth
  • Burning/stinging sensation
  • Skin irritation
  • Itching
  • Contact dermatitis
  • Dry skin
  • Mild discoloration of the skin (paling) at the site of application
  • Worsening of rosacea symptoms
  • Headache and/or dizziness

Some patients may experience worsening redness compared with their initial condition and appearance of redness in new areas of the face. This reaction can occur within hours after the application of the medicine or in several days or weeks after the beginning of treatment.

These adverse effects are temporary and usually mild. Contact your doctor in case of bothersome adverse effects that do not resolve during the expected period of time.

Using Erythego at Grant Pharmacy

Grant Pharmacy is committed to helping individuals achieve healthier, clearer skin. Our experienced pharmacists provide personalized guidance and support to patients using Erythego, ensuring optimal treatment outcomes and satisfaction.

Storage

Topical gel must keep in ideal room temperature and never access by any others easily.

You can keep the gel in a tightly closed container, away from sunlight, moisture, and others.

Store topical gel away from pets and children and safely discard expired topical gel.

When buying the brimonidine topical gel 0.33, patients must check the price from Grant online Pharmacy.

Interactions

Though the Brimonidine (Erythego) is applied topically, a certain amount of the medication enters into the bloodstream and can reduce blood pressure. Therefore, special caution should be exercised when Brimonidine is used in combination with antihypertensive drugs, cardiac glycosides, or other medications that cause lowering of blood pressure or heart rate. Patients can need monitoring for dizziness, weakness, fainting, and unusually slow heartbeat.

Alcohol, sedatives, opioids for pain relief, sleeping pills, sedating antihistamines, and other central nervous system depressants may enhance the effects causing tiredness, dizziness, and decreased alertness if enough brimonidine is absorbed.

Monoamine oxidase inhibitors may inhibit the metabolism of brimonidine and increase the occurrence of systemic effects. Tricyclic antidepressants may affect the sensitivity to medicines acting through adrenergic nervous system. Patients using tricyclic antidepressants should undergo evaluation of their medications list before the start of the treatment.

Special caution may be needed in individuals with severe/unstable cardiovascular disorders, low blood pressure, poor peripheral blood circulation, Raynaud's phenomenon, cerebral or coronary insufficiency, depression, and other diseases of blood vessels.

Inform your doctor and pharmacist about all the medications, supplements, and herbal products you take.

 

Frequently asked questions about Brimonidine Topical Gel 0.33% (Erythego) 15g (FAQs)

What are the problems to tell with the doctor when it comes to treatment with topical gel?

Patients must inform doctors about health issues before beginning treatment, like liver, heart, kidney disease and blood circulation problems. Patients also let physicians know whether they have open wounds and inflammation in the skin.

Is it suitable to apply around the eyes?

No, topical gel is only applicable for treating rosacea. Areas around the eyes are extremely sensitive. Patients must keep gel away from their eyelids and eyes. Whether gel contacts eyes accidentally, rinsing eyes with cold water is essential. If

Can patients stop using gel on their own?

No, patients never stop using on their own until the course of treatment. It may affect disease conditions severely. If you wish to stop using gel, you can consult a doctor. The doctor provides necessary guidelines and advises patients not to stop using gel unnecessarily during treatment. 

How long does topical gel take to reveal the outcome?

Topical gel works quickly on the affected area and gives peace of mind to people. They experience a good outcome very soon without waiting for too long time.

Medically reviewed by the Grant Pharmacy Pharmacists Medical Team

Medical References

FDA Prescribing Information – MIRVASO (Brimonidine) Topical Gel 0.33%
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/204708s005lbl.pdf

DailyMed – Brimonidine Topical Gel 0.33%
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c899b329-cc5e-4443-8e94-451314de47c9

MedlinePlus – Rosacea
https://medlineplus.gov/rosacea.html

Disclaimer: The medicine information provided on this page is for general knowledge purposes only. It is not intended to replace professional medical advice. Please consult your doctor or pharmacist before using any medicine.
- Grant Pharmacy

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